Biomimetic Biomaterials for Skin Regeneration

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Biomimetic Biomaterials for Skin Regeneration

Dolly Rani, Kalpana Swain, Satyanarayan Pattnaik

Skin regeneration is a complex biological process involving inflammation, cellular migration, and tissue remodeling. Biomimetic biomaterials, designed to replicate the structural and biochemical properties of the extracellular matrix, offer significant promise in enhancing wound healing. These materials incorporate bioactive molecules such as collagen, elastin, chitosan, and growth factors to support cellular functions. Emerging intelligent biomaterials responsive to environmental stimuli present new therapeutic avenues. The chapter explores recent innovations in biomimetic scaffolds, their interaction with the skin microbiome, and challenges in clinical translation. It emphasizes a multidisciplinary approach to advancing skin regeneration technologies tailored to patient-specific needs.

Keywords
Smart Biomaterials, Bioactive Compounds, Tissue Engineering, Wound Healing, Skin Regeneration, Extracellular Matrix Mimicry, Endogenous Regeneration, Biomimetic Biomaterials

Published online , 19 pages

Citation: Dolly Rani, Kalpana Swain, Satyanarayan Pattnaik, Biomimetic Biomaterials for Skin Regeneration, Materials Research Foundations, Vol. 193, pp 39-57, 2026

DOI: https://doi.org/10.21741/9781644904350-2

Part of the book on Biomimetic

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