Optimization of Mimosa Pudica Linn Extraction at Varied Feed to Solvent Ratios and Solvent Concentrations using Response Surface Methodology
Nurul Aishah ABDUL RAHIM, Sariah ABANG, Mohd Raziman ISMAIDI, Muhammad Abbas AHMAD ZAINI, Rubiyah BAINI, Sherena SAR-EE
Abstract. Mimosa pudica linn, a creeping plant with either annual or perennial flowering, is commonly known as Daun Semalu in Malaysia. This plant has gained worldwide recognition among researchers not only for its unique reaction upon touch, but also for its long-standing used in traditional medicine. In this study, Response surface methodology (RSM) was used to determine the ideal extraction conditions of the plant leaves by Soxhlet extraction. The study was conducted using ethanol as the solvent at three different concentrations (50%, 70% and 90%) with varied feed-to-solvent ratios (1:15, 1:17, 1:20). The highest extraction yield achieved is 18.61% at ratio of 1:20 with a solvent concentration of 90%. Whereby the optimum conditions predicted by RSM is at a feed-to-solvent ratio of 1:2 (0.05) and a solvent concentration of 89.59% which estimated an extraction yield of 18.72%. Further analyses using Fourier transform infrared spectroscopy (FTIR) and gas chromatography-mass spectrometry (GC-MS) were also conducted to identify the bioactive compounds present in the extracts. FTIR results indicated the presence of various functional groups such as phenolics, alcohol, and alkene groups, suggesting the presence of bioactive compounds. GC-MS analysis identified several key compounds, including benzene, phytol, and phenol, 2,4-bis(1-methyl-1-phenylethyl)-, which are known for their therapeutic properties.
Keywords
Mimosa Pudica Linn, Response Surface Methodology (RSM), Soxhlet Extraction
Published online 1/15/2026, 8 pages
Copyright © 2026 by the author(s)
Published under license by Materials Research Forum LLC., Millersville PA, USA
Citation: Nurul Aishah ABDUL RAHIM, Sariah ABANG, Mohd Raziman ISMAIDI, Muhammad Abbas AHMAD ZAINI, Rubiyah BAINI, Sherena SAR-EE, Optimization of Mimosa Pudica Linn Extraction at Varied Feed to Solvent Ratios and Solvent Concentrations using Response Surface Methodology, Materials Research Proceedings, Vol. 59, pp 154-161, 2026
DOI: https://doi.org/10.21741/9781644903957-20
The article was published as article 20 of the book Separation Technology
Content from this work may be used under the terms of the Creative Commons Attribution 3.0 license. Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI.
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