Significant Role of Polymers in the Field of Surgery
Niharika Kulshrestha
Polymers have unique features which make their wide application. The unique features of polymers such as high flexibility, durability, mechanical stability, light weight, easy to use, easily available, low cost etc. make them useable in various industrial, homely, electrochemical, electrical, electronics, medical, biomedical, surgery and food packaging. This chapter mainly focused on the application of polymers in the field of surgery. In the older methods, absence of polymers was facing limitations like decreased mechanical stability and low adherence to tissue surface. This chapter also discussed that different shape memory polymers can be used in surgery.
Keywords
Polymers, Surgery, Bio-medical, Shape Memory Polymers, Biopolymers
Published online 2/15/2025, 12 pages
Citation: Niharika Kulshrestha, Significant Role of Polymers in the Field of Surgery, Materials Research Foundations, Vol. 172, pp 187-198, 2025
DOI: https://doi.org/10.21741/9781644903353-7
Part of the book on Applications of Polymers in Surgery II
References
[1] Heitor, Luiz, Ornaghi., Francisco, Maciel, Monticeli., Lucas, Dall, Agnol. (2023). A Review on Polymers for Biomedical Applications on Hard and Soft Tissues and Prosthetic Limbs. Polymers. https://doi.org/10.3390/polym15194034.
[2] Metecan, Erdi., Anthony, D., Sandler., Peter, Kofinas. (2023). Polymer nanomaterials for use as adjuvant surgical tools.. Wiley Interdisciplinary Reviews-nanomedicine and Nanobiotechnology. https://doi.org/10.1002/wnan.1889.
[3] (2023). Polymers for surgical sutures. https://doi.org/10.1016/b978-0-12-819750-9.00004-8.
[4] Robert, D., Benson., Wei, He. (2024). Polymeric Biomaterials. https://doi.org/10.1016/b978-0-323-88667-3.00022-9.
[5] Yunhao, Chen., Muyuan, Chai., Chen, Xuan., Jiayi, Lin., Huishang, Yang., Chunhui, Li., Manshan, Xie., Serge, Ostrovidov., Xuetao, Shi., Chuanbin, Mao. (2024). 3. Tuning the properties of surgical polymeric materials for improved soft-tissue wound closure and healing. Progress in Materials Science. https://doi.org/10.1016/j.pmatsci.2024.101249
[6] (2022). 2. Applications of Polymers in Surgery. https://doi.org/10.21741/9781644901892
[7] (2023). 1. Polymers for surgical sutures. https://doi.org/10.1016/b978-0-12-819750-9.00004-8
[8] Shuko, Suzuki., Yoshito, Ikada. (2015). 5. Polymers for Surgery. https://doi.org/10.1007/978-3-319-12478-0_8
[9] Tudor, Bibire., Onur, Yilmaz., Cristina, Mihaela, Ghiciuc., Nela, Bibire., Radu, Danila. (2022). Biopolymers for Surgical Applications. Coatings. https://doi.org/10.3390/coatings12020211
[10] Fernando, Notario-Pérez., Araceli, Martín-Illana., Raúl, Cazorla-Luna., Roberto, Ruiz-Caro., María-Dolores, Veiga. (2022). Applications of Chitosan in Surgical and Post-Surgical Materials. Marine Drugs. https://doi.org/10.3390/md20060396
[11] Marios, Koutsoukos. (2022). The Role of Advanced Polymers in Surgery & Medical Devices. https://doi.org/10.21741/9781644901892-2
[12] Neta, Shimony., Alona, Shagan., Bat-hen, Eylon., Abraham, Nyska., Adi, Gross., Boaz, Mizrahi. (2021). Liquid Copolymers as Biodegradable Surgical Sealant.. Advanced Healthcare Materials. https://doi.org/10.1002/ADHM.202100803
[13] Maitz, M. F. (2015). Applications of synthetic polymers in clinical medicine. Biosurface and Biotribology, 1(3), 161-176.
[14] Annabi, N., Tamayol, A., Shin, S. R., Ghaemmaghami, A. M., Peppas, N. A., & Khademhosseini, A. (2014). Surgical materials: current challenges and nano-enabled solutions. Nano today, 9(5), 574-589.
[15] Jain, R., & Wairkar, S. (2019). Recent developments and clinical applications of surgical glues: An overview. International journal of biological macromolecules, 137, 95-106.
[16] Teo, A. J., Mishra, A., Park, I., Kim, Y. J., Park, W. T., & Yoon, Y. J. (2016). Polymeric biomaterials for medical implants and devices. ACS Biomaterials Science & Engineering, 2(4), 454-472.
[17] Guo, L., Liang, Z., Yang, L., Du, W., Yu, T., Tang, H., … & Qiu, H. (2021). The role of natural polymers in bone tissue engineering. Journal of Controlled Release, 338, 571-582.
[18] Rami, Matarneh., S., Sotnik., Vyacheslav, Lyashenko. (2018). Polymers in cardiovascular surgery. Asian Journal of Pharmaceutical and Clinical Research. https://doi.org/10.22159/AJPCR.2018.V11I5.24576
[19] Ernest, A., Azzopardi., R., Steven, Conlan., Iain, S., Whitaker. (2016). Polymer therapeutics in surgery: the next frontier.. https://doi.org/10.1002/JIN2.6
[20] Sapana, Jadoun., Sampath, Chinnam., Amir, Qureshi. (2023). Polymers in bone and orthopedic surgery. https://doi.org/10.1016/b978-0-12-823797-7.00019-8
[21] Metecan, Erdi., Anthony, D., Sandler., Peter, Kofinas. (2023). Polymer nanomaterials for use as adjuvant surgical tools.. Wiley Interdisciplinary Reviews-nanomedicine and Nanobiotechnology. https://doi.org/10.1002/wnan.1889
[22] (2023). Polymers for surgical sutures. https://doi.org/10.1016/b978-0-12-819750-9.00004-8
[23] İlkay, CİVELEK. (2022). Applications of Polymers in Neurosurgery. https://doi.org/10.21741/9781644901892-4
[24] Fernando, Notario-Pérez., Araceli, Martín-Illana., Raúl, Cazorla-Luna., Roberto, Ruiz-Caro., María-Dolores, Veiga. (2022). Applications of Chitosan in Surgical and Post-Surgical Materials. Marine Drugs. https://doi.org/10.3390/md20060396
[25] Notario-Pérez, F., Martín-Illana, A., Cazorla-Luna, R., Ruiz-Caro, R., & Veiga, M. D. (2022). Applications of chitosan in surgical and post-surgical materials. Marine drugs, 20(6), 396.
[26] Franco, R., Gianfreda, F., Miranda, M., Barlattani, A., & Bollero, P. (2020). The hemostatic properties of chitosan in oral surgery. Biomedical and Biotechnology Research Journal (BBRJ), 4(3), 186-188.
[27] Shuko, Suzuki., Yoshito, Ikada. (2015). Polymers for Surgery. https://doi.org/10.1007/978-3-319-12478-0_8
[28] Maitz, M. F. (2015). Applications of synthetic polymers in clinical medicine. Biosurface and Biotribology, 1(3), 161-176.
[29] Fernando, Notario-Pérez., Araceli, Martín-Illana., Raúl, Cazorla-Luna., Roberto, Ruiz-Caro., María-Dolores, Veiga. (2022). Applications of Chitosan in Surgical and Post-Surgical Materials. Marine Drugs. https://doi.org/10.3390/md20060396
[30] Paweł, Turek., Grzegorz, Budzik., Mariusz, Oleksy., Katarzyna, Bulanda. (2020). Polymer materials used in medicine processed by additive techniques. Polimery. https://doi.org/10.14314/POLIMERY.2020.7.2
[31] Sung, Woon, On., Seoung-Won, Cho., Soo-Hwan, Byun., Byoung-Eun, Yang. (2020). Bioabsorbable Osteofixation Materials for Maxillofacial Bone Surgery: A Review on Polymers and Magnesium-Based Materials.. Biomedicines. https://doi.org/10.3390/BIOMEDICINES8090300 [
[32] D., Rickert., Helmut, Steinhart., Andreas, Lendlein. (2020). Functional requirements for polymeric implant materials in head and neck surgery. Clinical Hemorheology and Microcirculation. https://doi.org/10.3233/CH-209212
[33] Jarosław, Witkowski., Witold, Wnukiewicz., Paweł, Reichert. (2016). Polymers as Carriers of Gentamicin in Traumatology and Orthopedic Surgery – Current State Of Knowledge. Polimery w medycynie. https://doi.org/10.17219/PIM/65053
[34] Anna, Fizia-Orlicz., Marta, Misiuk-Hojło. (2015). The Use of Polymers for Intraocular Lenses in Cataract Surgery. Polimery w medycynie. https://doi.org/10.17219/PIM/61978
[35] Laura, G., Gómez-Mascaraque., Raquel, Palao-Suay., Blanca, Vázquez. (2014). The Use of Smart Polymers in Medical Devices for Minimally Invasive Surgery, Diagnosis, and Other Applications. https://doi.org/10.1533/9780857097026.2.359
[36] Andreas, Lendlein., Muhammad, Yasar, Razzaq., C., Wischke., Karl, Kratz., Matthias, Heuchel., J., Zotzmann., Bernhard, Hiebl., A.T., Neffe., Marc, Behl. (2017). 1.27 Shape-Memory Polymers. https://doi.org/10.1016/B978-0-12-803581-8.10213-9
[37] Richard, I., Reid. (2011). A Comparative Analysis of Biomaterials Currently Used in Pelvic Reconstructive Surgery.
[38] Evangelos, Athanassiou., Nikolaos, C., Vamvakopoulos., Fani, Nakopoulou., Ioannis, Fezoulidis., Dimitrios, Zaharoulis., Michael, Spyridakis., Constantinos, Hatzitheofilou. (2009). Use of albumin polymers during breast cancer surgery improves postoperative seroma outcome.. Surgical technology international,
[39] Polyether-polyamide plastics, specifically Pebax, are utilized for surgical applications such as intraocular lens inserters due to their clean and labile oligomer-free properties.
[40] George, E., Snow. (2011). Polymer for surgeons gloves.
[41] Anju, Singhwane., Ayush, Jaiswal., Kamana, Chaturvedi., Medha, Mili., Kunal, Pal., Ranjan, K., Mohapatra., Mohd., Akram, Khan., Hari, Narayan, Bhargaw., A.K., Srivastava., S., Verma. (2023). Smart shape memory polymers and their significance in biomedical applications: A review. Polymers for Advanced Technologies. https://doi.org/10.1002/pat.6138
[42] Andreas, Lendlein., Muhammad, Yasar, Razzaq., C., Wischke., Karl, Kratz., Matthias, Heuchel., J., Zotzmann., Bernhard, Hiebl., A.T., Neffe., Marc, Behl. (2017). 1.27 Shape-Memory Polymers. https://doi.org/10.1016/B978-0-12-803581-8.10213-9
[43] Dinesh, Rokaya., Hans, Erling, Skallevold., Viritpon, Srimaneepong., Anand, Marya., Pravin, Kumar, Shah., Zohaib, Khurshid., Muhammad, Zafar., Janak, Sapkota. (2023). 8. Shape Memory Polymeric Materials for Biomedical Applications: An Update. Journal of composites science. https://doi.org/10.3390/jcs7010024.
[44] Luigi, De, Nardo., Sabrina, De, Cicco., Matteo, Jovenitti., Maria, Cristina, Tanzi., Silvia, Farè. (2006). 4. Shape Memory Polymer Porous Structures for Mini-Invasive Surgical Procedures. https://doi.org/10.1115/ESDA2006-95559
[45] Marc Behl, Andreas Lendlein, Shape-memory polymers, Materials Today,Volume 10, Issue 4, 2007,Pages 20-28,
[46] ISSN 1369-7021Liang, Chen., Yubai, Yuan., Rengfei, Shi. (2023). 3. The Current Status, Prospects, and Challenges of Shape Memory Polymers Application in Bone Tissue Engineering. Polymers. https://doi.org/10.3390/polym15030556
[47] Rory, O’Brien., Vicente, Moritz., Paul, McDonald., Declan, Devine., Rupal, Srivastava. (2023). 1. Design and Development of Shape Memory Polymer-Based Mechanical Thrombectomy Device. https://doi.org/10.1115/imece2023-113295.
[48] Ailifeire, Fulati., Koichiro, Uto., Masanobu, Iwanaga., Miho, Watanabe., Mitsuhiro, Ebara. (2022). 4. Smart Shape‐Memory Polymeric String for the Contraction of Blood Vessels in Fetal Surgery of Sacrococcygeal Teratoma. Advanced Healthcare Materials. https://doi.org/10.1002/adhm.202200050
[49] Janitha, Jeewantha., Sandaruwan, Jayalath., Chris, Emmanuel., Madhubhashitha, Herath., Elizabeth, Forster., Mainul, Islam., Jinsong, Leng., Jayantha, Ananda, Epaarachchi. (2022). 7. Shape memory polymer smart plaster for orthopaedic treatments. Smart Materials and Structures. https://doi.org/10.1088/1361-665X/ac943b
[50] P., A., Zhukova., Fedor, Senatov., M.Yu., Zadorozhnyy., N., S., Chmelyuk., V., A., Zaharova. (2021). 12. Polymer Composite Materials Based on Polylactide with a Shape Memory Effect for “Self-Fitting” Bone Implants. Polymers. https://doi.org/10.3390/POLYM13142367
[51] Emily, Dalton., Qinyuan, Chai., Molly, W., Shaw., Tucker, J., McKenzie., Eric, S., Mullins., Neil, Ayres. (2019). 14. Hydrogel-coated polyurethane/urea shape memory polymer foams. Journal of Polymer Science Part A. https://doi.org/10.1002/POLA.29398
[52] Xiaoqing, Yang., Zhipeng, Han., Chengqi, Jia., Tianjiao, Wang., Xiaomeng, Wang., Fanqi, Hu., Hui, Zhang., Jun, Zhao., Xuesong, Zhang. (2023). 16. Preparation and Characterization of Body-Temperature-Responsive Thermoset Shape Memory Polyurethane for Medical Applications. Polymers. https://doi.org/10.3390/polym15153193