Interactions of Nanoparticles with Lipid and Cell Membranes
Rohit Awale, Nilesh Kulkarni, Saurabh Khadse
The interactions between nanoparticles and lipid or cell membranes are of paramount importance in the realms of nanomedicine and nanotoxicology. Nanoparticles, with their unique physicochemical properties, exhibit dynamic interactions upon contact with biological membranes. These interactions include adsorption, penetration, and potential disruption of lipid bilayers. Such interactions play a crucial role in drug delivery systems, enabling precise targeting and controlled release of therapeutic agents. However, these interactions also raise concerns about nanoparticle toxicity due to potential membrane damage. A deeper understanding of these intricate processes is essential for harnessing the benefits of nanoparticles while ensuring their safety in biomedical applications.
Keywords
Nanoparticles, Cell Membranes, Nanoparticle Interactions, Lipid Bilayers, Cellular Uptake, Permeability, Protein Interactions, Membrane Structure
Published online 12/15/2024, 26 pages
Citation: Rohit Awale, Nilesh Kulkarni, Saurabh Khadse, Interactions of Nanoparticles with Lipid and Cell Membranes, Materials Research Foundations, Vol. 171, pp 191-216, 2024
DOI: https://doi.org/10.21741/9781644903339-7
Part of the book on Advances in Healthcare and Nanoparticle Toxicology
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