Interaction of Nanoparticles with Nucleic Acids
Sankara Rao Miditana, Saivenkatesh Korlam
The interaction of nanoparticles with nucleic acids has gained significant attention in recent years due to its potential applications in various fields, including gene therapy, biosensing, immunotherapy and drug delivery. The mechanisms of interaction between nanoparticles and nucleic acids are complex and involve multiple factors, including surface chemistry, size, and shape of nanoparticles. Once nanoparticles bind to nucleic acids, they can form complexes that can alter the physical and chemical properties of nucleic acids, leading to changes in their enzymatic activity and stability. The interaction between nanoparticles and nucleic acids also provides a promising avenue for targeted delivery of nucleic acids to specific cells or tissues.
Keywords
Drug Delivery, DNA, Gene Delivery, mRNA, Nucleic Acid, Nanoparticles
Published online 12/15/2024, 19 pages
Citation: Sankara Rao Miditana, Saivenkatesh Korlam, Interaction of Nanoparticles with Nucleic Acids, Materials Research Foundations, Vol. 171, pp 135-153, 2024
DOI: https://doi.org/10.21741/9781644903339-5
Part of the book on Advances in Healthcare and Nanoparticle Toxicology
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