Nanoparticles based Therapeutics Approaches for Cancer

Nanoparticles based Therapeutics Approaches for Cancer

Somya Ranjan Dash, Chanakya Nath Kundu

Surgery, chemotherapy, radiotherapy, targeted therapy and immunotherapy are all examples of standard cancer treatments. However, achieving successful cancer treatment is complicated by issues including insufficient selectivity, cytotoxicity, and chemo resistance. Nanotechnology’s introduction has brought about seismic shifts in the ways in which cancer is detected and treated. Biocompatibility, lower toxicity, better stability, increased permeability and retention effect, precision targeting, and other benefits of nanoparticles (NPs) make them a promising option for cancer therapy. This book chapter provides a comprehensive overview of both organic and inorganic NPs and how they might be used in the treatment of cancer. In addition, we have also emphasized various aspects of NPs targeting cancer stem cells (CSCs), reprogramming the tumor microenvironment (TME), cancer angiogenesis and how they can be utilized in overcoming drug resistance. Finally, the future of NPs in non-invasive cancer treatment has been discussed along with its potential risk to the environment.

Keywords
Nanoparticles in Cancer Therapy, Cancer Stem Cells Targeting, Tumor Microenvironment Reprogramming, Drug Resistance in Cancer, Non-Invasive Cancer Treatment

Published online 12/15/2024, 54 pages

Citation: Somya Ranjan Dash, Chanakya Nath Kundu, Nanoparticles based Therapeutics Approaches for Cancer, Materials Research Foundations, Vol. 171, pp 22-75, 2024

DOI: https://doi.org/10.21741/9781644903339-2

Part of the book on Advances in Healthcare and Nanoparticle Toxicology

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