Enzyme Immobilized Nanoparticles Towards Biosensor Fabrication
Jaison Jeevanandam, Sharadwata Pan, Michael K. Danquah
In recent times, nanomaterials with semiconductor properties are introduced as a potential transducer in biosensors, which can be credited to their intrinsic, elevated surface-to-volume proportion, enhanced sensitivity, and improved surface properties. The surface properties of nanomaterials have made them a significant transducer matrix towards the immobilization of bioreceptors, which eventually enhances the identification threshold and the biosensor sensing capability. Several nanomaterials, such as polymer, metal oxide, metal and carbon-based, as well as nanocomposites, are used towards transducer manufacturing, eventually being incorporated in the biosensors. The current chapter lays an outline with respect to biosensors that are fabricated with nanomaterials as a transducer, where enzymes acting as a bioreceptor, are immobilized on their surface. In addition, the biosensing mechanisms of the enzyme immobilized nanomaterials, their efficiency, detection limit, and sensitivity, are also discussed.
Keywords
Biosensor, Enzyme, Immobilization, Nanoparticles, Biomolecules, Nanocomposites
Published online , 20 pages
Citation: Jaison Jeevanandam, Sharadwata Pan, Michael K. Danquah, Enzyme Immobilized Nanoparticles Towards Biosensor Fabrication, Materials Research Foundations, Vol. 126, pp 142-161, 2022
DOI: https://doi.org/10.21741/9781644901977-5
Part of the book on Nanomaterial-Supported Enzymes
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