Theranostic Application of Nanoparticulated System: Present and Future Prospects

Theranostic Application of Nanoparticulated System: Present and Future Prospects

Rout George Kerry, Sabuj Sahoo, Gitishree Das, Jayanta Kumar Patra

Nano particulated systems are biocompatible materials or devices, engineered with a purpose to deliverer desired bioactive compounds to a targeted location without inducing any secondary reactions or side-effects. The diversified ability of this bioengineered molecule to breach the biological barriers to reach the targeted location in the biological system uplifts its other versatile nature of active distribution. Furthermore, its negligible toxicity and biodegradability has resulted in making it a unique candidate for its purpose as nanoparticulated system. These nano-based systems are currently exploited in conjugation to a heterogeneous array of bioactive natural phytochemicals or synthetic compounds as a therapy against various diseases or disorders. Some diseases or disorders include obesity, diabetes, liver fibrosis, cardiovascular disorders, neurodegenerative disorders, cancers of various forms and microbial infections. Despite of the ability of these nano-based systems to be a novel therapy against a number of diseases and disorders their utilization and commercialization is restrained. This procrastination could be relinquished if pertinent mechanisms of their molecular interactions are properly acknowledged. Henceforth the objective of the present paper is to provide an overview of the types of nano carriers employed in diversified nano particulated systems based on their theranostic application, beneficial as well as deleterious impacts, present status and future prospects.

Keywords
Nanocarriers, Bioconjugation, Biodistribution, Biocompatible, Diagnostics, Drug Delivery, Functionalize

Published online 3/25/2019, 48 pages

Citation: Rout George Kerry, Sabuj Sahoo, Gitishree Das, Jayanta Kumar Patra, Theranostic Application of Nanoparticulated System: Present and Future Prospects, Materials Research Foundations, Vol. 47, pp 241-288, 2019

DOI: https://doi.org/10.21741/9781644900130-7

Part of the book on Biosensors

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